Evaluation of the Effectiveness of Community-Level Interventions for the Rational Use of Antibiotics
Research Article
Open Access
CC BY

Evaluation of the Effectiveness of Community-Level Interventions for the Rational Use of Antibiotics

Jiaxin Tian 1*
1 Woodbridge school
*Corresponding author: 282201ella@gmail.com
Published on 2 October 2025
Journal Cover
TNS Vol.139
ISSN (Print): 2753-8826
ISSN (Online): 2753-8818
ISBN (Print): 978-1-80590-395-6
ISBN (Online): 978-1-80590-396-3
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Abstract

In recent years, the problem of antibiotic resistance resulting from misuse has become a prominent challenge threatening global public health security. As one of the most frequent settings for antibiotic use, the rationality of antibiotic usage in communities directly affects the overall effectiveness of resistance prevention and control. At present, the prevalence of self-medication misconceptions among residents, non-standard prescriptions by primary healthcare personnel, and illegal antibiotic sales in retail pharmacies in communities have increased the risk of irrational antibiotic use. Against this backdrop, this study focuses on community-level interventions for the rational use of antibiotics, systematically analyzing their significance in enhancing public awareness, standardizing prescription practices, and curbing the development of resistance. It further explores the mechanisms by which residents’ personal characteristics, community environmental conditions, and intervention design influence outcomes. Specific intervention measures—such as public education, healthcare personnel training, monitoring and feedback, and pharmacy supervision—are detailed, and their implementation effectiveness is comprehensively evaluated. The study aims to contribute to the construction of a scientific and efficient resistance prevention and control system, safeguarding public health and medical safety.

Keywords:

community, antibiotics, rational use, intervention measures, effectiveness evaluation

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Tian,J. (2025). Evaluation of the Effectiveness of Community-Level Interventions for the Rational Use of Antibiotics. Theoretical and Natural Science,139,49-55.

References

[1]. World Health Organization. Antimicrobial resistance: key facts. 2021. https: //www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance

[2]. Taylor L. COVID-19: antimicrobial misuse in Americas sees drug resistant infections surge, says WHO. BMJ, 2021; 375: n2845.

[3]. Mladenovic-Antic S, Kocic B, Velickovic-Radovanovic R, et al. Correlation between antimicrobial consumption and antimicrobial resistance of Pseudomonas aeruginosa in a hospital setting: a 10-year study. J Clin Pharm Ther, 2016; 41: 532–537.

[4]. Rawson TM, Moore LSP, Zhu N, et al. Bacterial and fungal coinfection in individuals with coronavirus: a rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis, 2020; 71: 2459–2468.

[5]. Lobie TA, Roba AA, Booth JA, et al. Antimicrobial resistance: a challenge awaiting the post-COVID-19 era. Int J Infect Dis, 2021; 111: 322–325.

[6]. Abelenda-Alonso G, Padullés A, Rombauts A, et al. Antibiotic prescription during the COVID-19 pandemic: a biphasic pattern. Infect Control Hosp Epidemiol, 2020; 41: 1371–1372.

[7]. Hendriksen RS, Munk P, Njage P, et al. Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. Nat Commun, 2019; 10: 1124.

[8]. Adebisi YA, Alaran AJ, Okereke M, et al. COVID-19 and antimicrobial resistance: a review. Infect Dis, 2021; 14: 11786337211033870.

[9]. Seethalakshmi PS, Charity OJ, Giakoumis T, et al. Delineating the impact of COVID-19 on antimicrobial resistance: an Indian perspective. Sci Total Environ, 2022; 818: 151702.

[10]. Cassini E, Pezzani MD. Public health burden of antimicrobial resistance in Europe. Lancet Infect Dis, 2019; 19: 4–6.

References

[1]. World Health Organization. Antimicrobial resistance: key facts. 2021. https: //www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance

[2]. Taylor L. COVID-19: antimicrobial misuse in Americas sees drug resistant infections surge, says WHO. BMJ, 2021; 375: n2845.

[3]. Mladenovic-Antic S, Kocic B, Velickovic-Radovanovic R, et al. Correlation between antimicrobial consumption and antimicrobial resistance of Pseudomonas aeruginosa in a hospital setting: a 10-year study. J Clin Pharm Ther, 2016; 41: 532–537.

[4]. Rawson TM, Moore LSP, Zhu N, et al. Bacterial and fungal coinfection in individuals with coronavirus: a rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis, 2020; 71: 2459–2468.

[5]. Lobie TA, Roba AA, Booth JA, et al. Antimicrobial resistance: a challenge awaiting the post-COVID-19 era. Int J Infect Dis, 2021; 111: 322–325.

[6]. Abelenda-Alonso G, Padullés A, Rombauts A, et al. Antibiotic prescription during the COVID-19 pandemic: a biphasic pattern. Infect Control Hosp Epidemiol, 2020; 41: 1371–1372.

[7]. Hendriksen RS, Munk P, Njage P, et al. Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. Nat Commun, 2019; 10: 1124.

[8]. Adebisi YA, Alaran AJ, Okereke M, et al. COVID-19 and antimicrobial resistance: a review. Infect Dis, 2021; 14: 11786337211033870.

[9]. Seethalakshmi PS, Charity OJ, Giakoumis T, et al. Delineating the impact of COVID-19 on antimicrobial resistance: an Indian perspective. Sci Total Environ, 2022; 818: 151702.

[10]. Cassini E, Pezzani MD. Public health burden of antimicrobial resistance in Europe. Lancet Infect Dis, 2019; 19: 4–6.

Cite this article

Tian,J. (2025). Evaluation of the Effectiveness of Community-Level Interventions for the Rational Use of Antibiotics. Theoretical and Natural Science,139,49-55.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

About volume

Volume title: Proceedings of ICBioMed 2025 Symposium: AI for Healthcare: Advanced Medical Data Analytics and Smart Rehabilitation

ISBN: 978-1-80590-395-6(Print) / 978-1-80590-396-3(Online)
Editor: Alan Wang
Conference website: https://2025.icbiomed.org/auckland.html
Conference date: 17 October 2025
Series: Theoretical and Natural Science
Volume number: Vol.139
ISSN: 2753-8818(Print) / 2753-8826(Online)

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