Chemical Synthesis of Uvarialeptone B

Jinlai Liu

doi:10.54254/2755-2721/2025.29780

Applied and Computational EngineeringOpen access

Chemical Synthesis of Uvarialeptone B

Research Article

Open Access

Chemical Synthesis of Uvarialeptone B

Jinlai Liu ^1*

¹ High School Attached to Northeast Normal University,

^*Corresponding author: gomo13113@gmail.com

Published on 19 November 2025

ACE Vol.208

ISSN (Print): 2755-273X

ISSN (Online): 2755-2721

ISBN (Print): 978-1-80590-547-9

ISBN (Online): 978-1-80590-548-6

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Abstract

Uvarialeptone B has the ability to kill and inhibit the growth of cancer cells. In this study, a retrosynthetic analysis and a synthetic method will be listed and found, using some traditional organic chemical reactions, such as Fleming-Tamao oxidation and DA reaction. It is the aim of this essay to propose a synthetic method to produce uvarialeptone B.

Keywords:

retrosynthesis, uvarialeptone B, DA Reaction, Tamao-Fleming Oxidation

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References

[1]. Tetrahydroxanthene-1, 3(2H)diones and Oxidized Hexadiene Derivatives from Uvaria leptopoda and Their Biological Activities https: //pubmed.ncbi.nlm.nih.gov/38805684/

[2]. NP-MRD Showing NP-Card of Uvarialeptone B (NP0333241) https: //np-mrd.org/natural_products/NP0333241

[3]. Wikipedia, Diels–Alder reaction https: //en.wikipedia.org/wiki/Diels%E2%80%93Alder_reaction

[4]. Wikipedia, Fleming-Tamao Oxidationhttps: //en.wikipedia.org/wiki/Fleming%E2%80%93Tamao_oxidation

References

[1]. Tetrahydroxanthene-1, 3(2H)diones and Oxidized Hexadiene Derivatives from Uvaria leptopoda and Their Biological Activities https: //pubmed.ncbi.nlm.nih.gov/38805684/

[2]. NP-MRD Showing NP-Card of Uvarialeptone B (NP0333241) https: //np-mrd.org/natural_products/NP0333241

[3]. Wikipedia, Diels–Alder reaction https: //en.wikipedia.org/wiki/Diels%E2%80%93Alder_reaction

[4]. Wikipedia, Fleming-Tamao Oxidationhttps: //en.wikipedia.org/wiki/Fleming%E2%80%93Tamao_oxidation

Cite this article

Liu,J. (2025). Chemical Synthesis of Uvarialeptone B. Applied and Computational Engineering,208,48-53.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

About volume

Volume title: Proceedings of the 5th International Conference on Materials Chemistry and Environmental Engineering

ISBN: 978-1-80590-547-9(Print) / 978-1-80590-548-6(Online)

Editor: Ömer Burak İSTANBULLU

Conference website: https://2025.confmcee.org/

Conference date: 12 January 2026

Series: Applied and Computational Engineering

Volume number: Vol.208

ISSN: 2755-2721(Print) / 2755-273X(Online)

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