Review on Biological-based Hydrogels for Advanced Applications
Research Article
Open Access
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Review on Biological-based Hydrogels for Advanced Applications

Yutao Zhang 1*
1 National University of Singapore
*Corresponding author: e1373388@u.nus.edu
Published on 27 June 2025
Journal Cover
ACE Vol.171
ISSN (Print): 2755-273X
ISSN (Online): 2755-2721
ISBN (Print): 978-1-80590-219-5
ISBN (Online): 978-1-80590-220-1
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Abstract

Bio-based hydrogels, derived from natural materials such as chitosan, alginate, gelatin, and collagen, have garnered significant attention for their outstanding biocompatibility and ability to mimic natural tissues. This review examines commonly used preparation methods, including physical, chemical and hybrid cross-linking, along with their primary components, such as polysaccharides and proteins. Owing to their flexibility and responsiveness, these hydrogels are widely used in areas such as soft robotics, cancer therapy and biosensing. However, despite promising advancements, significant challenges persist, particularly regarding their limited strength and stability. Future research should aim to enhance the performance and reliability of these materials to support their integration into complex medical and engineering systems.

Keywords:

Bio-based hydrogels, Biocompatibility, Cross-linking methods, Polysaccharides and proteins, Biomedical applications

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Zhang,Y. (2025). Review on Biological-based Hydrogels for Advanced Applications. Applied and Computational Engineering,171,21-32.

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Cite this article

Zhang,Y. (2025). Review on Biological-based Hydrogels for Advanced Applications. Applied and Computational Engineering,171,21-32.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

About volume

Volume title: Proceedings of the 3rd International Conference on Functional Materials and Civil Engineering

ISBN: 978-1-80590-219-5(Print) / 978-1-80590-220-1(Online)
Editor: Anil Fernando
Conference website: https://2025.conffmce.org/
Conference date: 24 October 2025
Series: Applied and Computational Engineering
Volume number: Vol.171
ISSN: 2755-2721(Print) / 2755-273X(Online)

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